The Health Care Act of 2010 (Health Care Act) is perhaps the most far-reaching legislation in a generation. It was designed to reform fundamentally the entire U.S. health care system. Once this legislation is fully implemented, it will have a major impact on virtually every business and individual by requiring the majority of U.S. residents not covered by Medicaid or Medicare to obtain health care coverage either individually or through his or her employer. This article outlines important Federal tax changes contained in this recent legislation.